A straightforward approach towards glycoamino acids and glycopeptides via Pd-catalysed allylic alkylation.
نویسندگان
چکیده
Chelated enolates are versatile nucleophiles for palladium-catalysed allylic alkylations. Even with complex allylic substrates the reaction proceed without significant isomerisation. This allows the stereoselective introduction of polyhydroxylated allylic sidechains into amino acids and peptides with retention of the olefin geometry.
منابع مشابه
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 7 1 شماره
صفحات -
تاریخ انتشار 2009